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Human Prolyl 4-Hydroxylase, beta Polypeptide (P4HB)

  • Serial No. GA-P0038HU
    Species Human
    Specification 0.1 mg/0.2mg
    Brand GenAsia
    Origin Shanghai
    Price US$350/US$620
    Detailed information
    1 Host: Escherichia coli (E. coli)
    2 Species: Human
    3 Protein Type: Recombinant
    4 Synonyms: CG6988, Dmel\\CG6988, Dpdi, EP(3)1022, PDI, dpdi, pdi, XPDIp, DSI, GIT, PHDB, PDIA1, PO4DB, PO4HB, PROHB, ERBA2L, P4Hbeta, Thbp, ERp59, Pdia1, PDIR, p55
    5 Purity: 95% by SDS-PAGE
    6 Application: WB、 Elisa、 Functional Studies
    7 Background:
    Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide bonds formation, reduction, or isomerization of newly synthesized proteins in the lumen of the endoplasmic reticulum (ER). Human Protein Disulfide Isomerase is involved in disulphide-bond formation and isomerization, as well as the reduction of disulphide bonds in proteins. PDI has been found to have moderate effects (25-fold) on the rate of oxidative folding of proteins in vitro. Recombinant Human PDI produced in E. coli is a single, non-glycosylated, polypeptide chain containing 508 AA and having a molecular mass of 57.1 kDa. The human PDI contains N-terminal 6xHis-tag and is purified by proprietary chromatographic techniques.
    8 Storage&Stability:
    Avoid repeated freeze and thaw cycle.Store at 2-8℃ for delivery and store at -20 or -70℃ for future use. The loss rate of the target protein which describes the stability was determined by accelerated thermal degradation test.That is to incubate the protein at 37℃ for 48h and no obvious degradation and precipitation were observed.The loss of this protein is less than 5% within the expiration date under appropriate storage condition.